Diet Science

Saccharomyces boulardii is a strain of probiotic yeast that was first isolated from the superfoods mangosteen and lychee fruit in 1923 by the French scientist Henri Boulard (hence the name). Today it is considered a "super probiotic" due to its unique properties and wide range of health benefits that set it apart from many other probiotic strains. Listen in this week as Dee discusses the key reasons why S. boulardii holds this distinction.Link to Saccharomyces boulardii supplement: https://amzn.to/4cVqkVuReferences:Kaźmierczak-Siedlecka, K., Ruszkowski, J., Fic, M., Folwarski, M., & Makarewicz, W. (2020). Saccharomyces boulardii CNCM I-745: A non-bacterial microorganism used as probiotic agent in supporting treatment of selected diseases. Current Microbiology, 77(9), 1987–1996. https://link.springer.com/article/10.1007/s00284-020-02053-9

Studies show that obese individuals have more Firmicutes and fewer Bacteroidetes in their gut bacteria compared to those who are not overweight. Research suggests that consuming apple cider vinegar (ACV) can help improve this ratio. Listen in this week as Dee explains ACV's impact on the gut microbiome and its role in weight loss.Link to Dee's Apple Cider Vinaigrette recipe: https://processedfreeamerica.org/dees-olive-oil-apple-cider-vinaigrette/References:Bouderbala, H., Dib, W., Kheroua, O., Saidi, D., & Kaddouri, H. (2019). Modulation of the intestinal microbiota by apple cider vinegar in rats subjected to cafeteria diet. Archives of Cardiovascular Diseases Supplements,11(3), e373-e374.https://doi.org/10.1016/j.acvdsp.2019.05.102Davis C. D. (2016). The gut microbiome and its role in obesity. Nutrition Today, 51(4), 167-174. https://doi.org/10.1097/NT.0000000000000167

Trimethylamine-N-oxide (TMAO) is a harmful compound produced by gut bacteria. Elevated TMAO levels can significantly influence the development of heart disease, type 2 diabetes, chronic kidney disease, cancer, and fatty liver disease. Listen in this week as Dee explains which foods increase the production of TMAO in the gut, and how you can optimize the health of your gut.References:Li, X. S., Obeid, S., Klingenberg, R., Gencer, B., Mach, F., Räber, L., Windecker, S., Rodondi, N., Nanchen, D., Muller, O., Miranda, M. X., Matter, C. M., Wu, Y., Li, L., Wang, Z., Alamri, H. S., Gogonea, V., Chung, Y. M., Tang, W. H., Hazen, S. L., … Lüscher, T. F. (2017). Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors. European Heart Journal, 38(11), 814–824. https://doi.org/10.1093/eurheartj/ehw582Shan, Z., Sun, T., Huang, H., Chen, S., Chen, L., Luo, C., Yang, W., Yang, X., Yao, P., Cheng, J., Hu, F. B., &

The term "planetary health" refers to the natural systems that are essential for the health and survival of the human population. A commission of leading scientists from 16 countries have developed a "flexitarian" type diet designed to optimize human health and environmental sustainability on Earth. Listen in this week as Dee explains the parameters of the Planetary Health Diet and how it can improve your health.Reference:Healthy diets from sustainable food systems: Summary report of the EAT-Lancet Commission. (n.d.). https://eatforum.org/content/uploads/2019/07/EAT-Lancet_Commission_Summary_Report.pdf

A study examining ancient mummies from various countries revealed that one-third of them had atherosclerosis (plaques in the arteries), a precursor to heart disease, regardless of following Paleo-type or Mediterranean-type diets. This ratio mirrors what we see in modern populations. Listen in this week as Dee uncovers how we can harness the power of diet to overcome our genetic predispositions and lead healthier, heart-friendly lives.Reference:Thompson, R. C., Allam, A. H., Lombardi, G. P., Wann, L. S., Sutherland, M. L., Sutherland, J. D., Soliman, M. A.-T., Frohlich, B., Mininberg, D. T., Monge, J. M., Vallodolid, C. M., Cox, S. L., Abd el-Maksoud, G., Badr, I., Miyamoto, M. I., el-Halim Nur el-din, A., Narula, J., Finch, C. E., & Thomas, G. S. (2013). Atherosclerosis across 4000 years of human history: The horus study of four ancient populations. The Lancet, 381(9873), 1211–1222. https://doi.org/10.1016/s0140-6736(13)60598-x 

A new study shows that a high-fat diet suppresses the expression of a protein called Jak3, which causes a cascade of inflammation that starts in the intestine, moves through the liver and on to the brain, ultimately causing Alzheimer's-like symptoms. Listen in this week as Dee discusses the results of this study and what it means for your health.References:Kumar, N., Mishra, J., Morales, R., & Kumar, P. (2024). Kinases in Gut-Liver-brain communication and neuroinflammation. Journal of Biological Chemistry, 300(3), 106750. https://www.jbc.org/article/S0021-9258(24)01223-7/fulltext

Glucagon-like peptide-1 (GLP-1) is a hormone naturally produced in the intestines during meals. It helps regulate blood sugar and weight by increasing insulin, slowing stomach emptying, and promoting fullness. Medications like Ozempic® and Wegovy® mimic the effects of GLP-1 but can be expensive and have unpleasant side effects. Listen in this week as Dee explores research on foods and probiotics that naturally boost GLP-1, offering similar benefits without the high costs and side effects.References:De Silva, A., & Bloom, S. R. (2012). Gut hormones and appetite control: A focus on PYY and GLP-1 as therapeutic targets in obesity. Gut and Liver, 6(1), 10–20. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286726/Hira, T., Trakooncharoenvit, A., Taguchi, H.;,Hara, H. (2021). Improvement of glucose tolerance by food factors having glucagon-like peptide-1 releasing activity. International Journal of Molecular Sciences, 22(12), 6623. https://www.mdpi.com/1422-0067/22/12/6623Perraudeau, F., McMurdie, P., Bullard, J

A study published in the British medical journal BMJ pooled data from 14 studies involving nearly 10 million people to look at connections between consumption of ultra-processed foods and various health outcomes. Listen in this week as Dee discusses the findings of this massive study and what it means for your health.Reference:Lane, M. M., Gamage, E., Du, S., Ashtree, D. N., McGuinness, A. J., Gauci, S., Baker, P., Lawrence, M., Rebholz, C. M., Srour, B., Touvier, M., Jacka, F. N., O’Neil, A., Segasby, T., & Marx, W. (2024). Ultra-processed food exposure and adverse health outcomes: Umbrella review of epidemiological meta-analyses. BMJ,384, e077310. https://www.bmj.com/content/384/bmj-2023-077310

Gugulipid, also known as gum guggul, is an extract of the resin from a West Indian tree that has documented cholesterol lowering properties. Listen in this week as Dee discusses the specific compounds in gugulipid that decrease elevated cholesterol and triglycerides, and the proper way to take this effective supplement.References: Urizar, N. L., & Moore, D. D. (2003). Guguglipd: A natural cholesterol-lowering agent. Annual Review of Nutrition, 23, 303–313. https://doi.org/10.1146/annurev.nutr.23.011702.073102 Link to Guggul Supplement (2 capsules per day provides 75 mg guggulsterone*): https://amzn.to/3UWZDI0

In a recent study, researchers found that the diet of some ancient hunter-gatherers primarily ate plant foods, including beans and grains, with only a small percentage of meat in their diet. This new understanding contrasts with the meat-centric modern Paleo diet. Listen in this week as Dee discusses the findings of the study, and what it means for your health.References:Moubtahij, Z., McCormack, J., Bourgon, N., Trost, M., Sinet-Mathiot, V., Fuller, B. T., Smith, G. M., Temming, H., Steinbrenner, S., Hublin, J.-J., Bouzouggar, A., Turner, E., & Jaouen, K. (2024). Isotopic evidence of high reliance on plant food among later Stone age hunter-gatherers at Taforalt, Morocco. Nature Ecology & Evolution, 8(5), 1035–1045. https://doi.org/10.1038/s41559-024-02382-z 

HDL is an acronym for "high-density lipoproteins"--compounds made in the body that are considered the "good guys" in the cholesterol game. They help to keep the "bad cholesterol" from building up and forming plaque in the arteries. Having high levels of HDL reduces the risk for both heart disease and stroke. Listen in this week as Dee elevates your understanding of cholesterol and explores natural strategies to boost your HDL levels.References:Stadler, J. T., & Marsche, G. (2021). Dietary strategies to improve cardiovascular health: Focus on increasing high-density lipoprotein functionality. Frontiers in Nutrition, 8. https://www.frontiersin.org/articles/10.3389/fnut.2021.761170/full

Bergamot, a citrus fruit hailing from the groves of southern Italy’s Calabria region, has been shown in clinical trials to lower bad cholesterol and triglycerides, and increase good cholesterol. Listen in in this week as Dee discusses the results of clinical studies using bergamot and the virtues of this super fruit.Reference:Lamiquiz-Moneo, I., Giné-González, J., Alisente, S., Bea, A. M., Pérez-Calahorra, S., Marco-Benedí, V., … Mateo-Gallego, R. (2020). Effect of bergamot on lipid profile in humans: A systematic review. Critical Reviews in Food Science and Nutrition, 60(18), 3133–3143. https://doi.org/10.1080/10408398.2019.1677554Link to purchase Bergamot: https://amzn.to/3wwO9mf

In 2015 a research team at UC Riverside found that soybean oil consumption induces obesity, diabetes, insulin resistance, and fatty liver in mice. Now, a new study by the same team shows that oil could also affect genes in the brain related to conditions like autism, Alzheimer's disease, anxiety, and depression. Listen in this week as Dee discusses the details of this study and how the changes in microbiome caused by soybean oil consumption are linked to negative iimpact on brain function.Reference:Martinez-Lomeli, J., Deol, P., Deans, J. R., Jiang, T., Ruegger, P., Borneman, J., & Sladek, F. M. (2023). Impact of various high fat diets on gene expression and the microbiome across the mouse intestines. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-49555-7  

A recent study conducted at the University of Texas MD Anderson Cancer Center showed that patients with a history of colorectal cancer who added a cup of navy beans daily to their regular meals saw positive changes in their gut microbiome after just 4 weeks. Listen in this week as Dee discusses the details of this study and how the changes in microbiome aid in colorectal cancer prevention and treatment.Reference:Zhang, X., Irajizad, E., Hoffman, K. L., Fahrmann, J. F., Li, F., Seo, Y. D., Browman, G. J., Dennison, J. B., Vykoukal, J., Luna, P. N., Siu, W., Wu, R., Murage, E., Ajami, N. J., Mcquade, J. L., Wargo, J. A., Long, J. P., Do, K.-A., Lampe, J. W., … Daniel, C. R.. (2023). Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: Insights from the BE GONE trial. Ebiomedicine, 98, 104873. https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00439-5/fulltext

Autophagy is a natural biochemical self-preservation process whereby the body cleans out damaged cells in order to regenerate newer, healthier cells. There are certain diet and lifestyle factors that aid or inhibit autophagy, leading either to improved health or accelerated degeneration.  Listen in this week as Dee discusses the mechanisms of autophagy and the best ways to ensure its optimal benefits.Reference:Aman, Y., Schmauck-Medina, T., Hansen, M., Morimoto, R. I., Simon, A. K., Bjedov, I., Palikaras, K., Simonsen, A., Johansen, T., Tavernarakis, N., Rubinsztein, D. C., Partridge, L., Kroemer, G., Labbadia, J., & Fang, E. F. (2021). Autophagy in healthy aging and disease. Nature Aging, 1(8), 634–650. https://www.nature.com/articles/s43587-021-00098-4#

Buckwheat honey is a type of honey produced by bees that collect nectar solely from the flowers of the buckwheat plant. This gives the honey a unique flavor and much higher antioxidant levels than clover or other types of honey. Listen in this week as Dee discusses the many unique health benefits of buckwheat honey!Link to purchase buckwheat honey: https://amzn.to/4apKkhr

Atrial Fibrillation (AFib), or an irregular heartbeat, is a condition that can lead to stroke, heart failure, and blood clots. A new study has found that drinking diet sodas puts you at a 20% higher risk for AFib. Listen in this week as Dee discusses the results of the study, and how much diet soda per week poses the highest risk.Reference:Sun, Y., Yu, B., Yu, Y., Wang, B., Tan, X., Lu, Y., Wang, Y., Zhang, K., & Wang, N. (2024). Sweetened beverages, genetic susceptibility, and incident atrial fibrillation: A Prospective cohort study. Circulation: Arrhythmia and Electrophysiology, 17(3). https://www.ahajournals.org/doi/10.1161/CIRCEP.123.012145

The Environmental Working Group's 2024 Shopper’s Guide to Pesticides in Produce™ (aka the Dirty Dozen and Clean 15 List) was released on March 20, 2024, and the results are shocking! Listen in this week as Dee talks about the list, what it means for your health, and how to strategize your grocery budget to ensure the least amount of pesticide exposure.Get the Guide at https://www.ewg.org/foodnews/

A recent study shines light on the profound impact of diet on chronic pain. Listen in this week as Dee discusses the findings of the study, and the strong undercurrent of desire among chronic pain sufferers to adopt healthier eating practices.Reference: Dong, H. J., Brain, K., Olsson, M., Dragioti, E., Gerdle, B., & Ghafouri, B. (2024). Eating habits and the desire to eat healthier among patients with chronic pain: A registry-based study. Scientific Reports, 14(1), 4705. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897138/Video Link: Dee Talks About Nutrition Changes for Gout: https://processedfreeamerica.org/dee-talks-about-gout/

A recent study shines light on the profound impact of diet on chronic pain. Listen in this week as Dee discusses the findings of the study, and the strong undercurrent of desire among chronic pain sufferers to adopt healthier eating practices.Reference: Dong, H. J., Brain, K., Olsson, M., Dragioti, E., Gerdle, B., & Ghafouri, B. (2024). Eating habits and the desire to eat healthier among patients with chronic pain: A registry-based study. Scientific Reports, 14(1), 4705. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10897138/Video Link: Dee Talks About Nutrition Changes for Gout: https://processedfreeamerica.org/dee-talks-about-gout/